Comparison of angioscopic findings between coronary balloon and laser angioplasty

Fabrice S. Larrazet; Patrick J. Dupouy; Jean Luc Dubois-Rande; Akira Hirosaka; Jan Kvasnicka; Herbert J. Geschwind M.D.

doi:10.1117/12.179913

12 July 1994 Comparison of angioscopic findings between coronary balloon and laser angioplasty

Fabrice S. Larrazet, Patrick J. Dupouy, Jean Luc Dubois-Rande, Akira Hirosaka, Jan Kvasnicka, Herbert J. Geschwind M.D.

Proceedings Volume 2130, Diagnostic and Therapeutic Cardiovascular Interventions IV; (1994) https://doi.org/10.1117/12.179913
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

Percutaneous intracoronary angioscopy was used to study the morphological changes occurring in coronary arteries after balloon or laser angioplasty. Angioscopy is thought to provide details on the coronary vessel lumen and the inner wall. Coronary lesion were studied in 44 patients with a 4.5 F Imagecath angioscope before and after each interventional procedure. Balloon and laser angioplasty were performed on 21 (group I) and 23 patients (group II), respectively. There was no difference in age, sex, or angiographic lesion appearance before the procedure between the two groups. Circumferential visualization of the target lesion was successfully completed in 17 group I patients and 19 group II patients. A larger lumen than that observed at control was seen in all 17 dilatation patients and in 13 of the 19 laser patients. Tissue remnants were observed in all balloon and laser patients. Laser irradiation resulted in characteristic sharp edged craters. Dissection was identified in 2 of 19 before versus 9 of 19 patients after balloon angioplasty (p<0.05) and in 0 of 23 before versus 4 of 23 patients after laser angioplasty. Subintimal hemorrhage was observed in 3 of 19 before versus 11 of 19 patients after balloon angioplasty (p<0.05) and in 2 of 23 before versus 4 of 23 patients after laser angioplasty. The frequency of hemorrhage was higher in the post balloon group than in the post laser group (11 of 19 versus 4 of 23, respectively, p<0.02). Angioscopy provides valuable information on lesion morphology after coronary interventions. Balloon dilation results in a high rate of dissection and subintimal hemorrhage. Laser angioplasty is able to ablate obstructing tissue and results in a lower rate of subintimal hemorrhage than balloon dilatation.

Citation Download Citation

Fabrice S. Larrazet, Patrick J. Dupouy, Jean Luc Dubois-Rande, Akira Hirosaka, Jan Kvasnicka, and Herbert J. Geschwind M.D. "Comparison of angioscopic findings between coronary balloon and laser angioplasty", Proc. SPIE 2130, Diagnostic and Therapeutic Cardiovascular Interventions IV, (12 July 1994); https://doi.org/10.1117/12.179913

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KEYWORDS

Laser therapeutics

Arteries

Angiography

Excimer lasers

Laser tissue interaction

Laser ablation

Visualization

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