Fiber optic sensor for general anesthetics based on Raman spectroscopy

Hillary L. MacDonald; Hao Liu; Paul Yager

doi:10.1117/12.180750

28 July 1994 Fiber optic sensor for general anesthetics based on Raman spectroscopy

Hillary L. MacDonald, Hao Liu, Paul Yager

Proceedings Volume 2131, Biomedical Fiber Optic Instrumentation; (1994) https://doi.org/10.1117/12.180750
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

Vibrational spectroscopy and chemometrics together can be used to identify and quantify low concentrations of small molecules, but the Raman effect has been considered too weak to be employed for remote fiber optic sensing of such gases. Preliminary data are presented suggesting that it is possible to enhance Raman signals of gases from a small probe. Polymers that have large partition coefficients for small nonpolar molecules such as general anesthetics can be used as selective absorbents for these gases. As long as the polymers do not luminesce or Raman scatter at interfering frequencies, they increase the signal-to-noise ratio of signals from absorbed molecules. Multipass cells are often used to enhance Raman scattering from gases. Forming an absorbent polymer into a ring with one or more optical `taps' allows recirculation of the excitation light, and extraction of the contrarotating Raman scattered light. Such a ring could be the basis of a small probe to be connected to a compact Raman instrument by optical fibers. These two methods of amplification improve signal-to-noise ratio, extend sensing range, and reduce both instrumental complexity and cost of sensors.

Citation Download Citation

Hillary L. MacDonald, Hao Liu, and Paul Yager "Fiber optic sensor for general anesthetics based on Raman spectroscopy", Proc. SPIE 2131, Biomedical Fiber Optic Instrumentation, (28 July 1994); https://doi.org/10.1117/12.180750

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