Imaging in biological tissues by means of diffraction tomography with photon density waves

Andreas H. Hielscher; Frank K. Tittel; Steven L. Jacques

doi:10.1117/12.200865

31 January 1995 Imaging in biological tissues by means of diffraction tomography with photon density waves

Andreas H. Hielscher, Frank K. Tittel, Steven L. Jacques

Proceedings Volume 2326, Photon Transport in Highly Scattering Tissue; (1995) https://doi.org/10.1117/12.200865
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

In biological tissues it is possible to generate photon density waves with wavelength below 5 cm. When these kind of waves encounter optical inhomogeneities with diameters in the millimeter and centimeter range, typical scattering effects occur. These scattering effects can be compared to the well known effect of ultrasound scattering. Ultrasound gets scattered at regions with different compressibility and density, while photon density waves are scattered at regions with different absorption and scattering coefficient. In this study, analytical solutions for the time dependent photon diffusion equation are used to estimate photon density wave diffraction effects caused by spherical optical inhomogeneities. The detectability of tumors and hemorrhages in the brain, based on the diffraction pattern generated by these heterogeneities, is discussed in detail.

Citation Download Citation

Andreas H. Hielscher, Frank K. Tittel, and Steven L. Jacques "Imaging in biological tissues by means of diffraction tomography with photon density waves", Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); https://doi.org/10.1117/12.200865

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