Photoablation with the free-electron laser in the far IR in biological soft tissue (cornea)

Rudolf Walker; Manfred Ostertag; Thomas Bende; P. Wim van Amersfoort; Benedikt J. Jean M.D.

doi:10.1117/12.209875

22 May 1995 Photoablation with the free-electron laser in the far IR in biological soft tissue (cornea)

Rudolf Walker, Manfred Ostertag, Thomas Bende, P. Wim van Amersfoort, Benedikt J. Jean M.D.

Proceedings Volume 2391, Laser-Tissue Interaction VI; (1995) https://doi.org/10.1117/12.209875
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

Wavelengths in the range from 12 micrometers up to 70 micrometers (far IR) have a water absorption coefficient in the same order as wavelengths used successfully for ablation near the 6 micrometers water absorption peak. Thus these wavelengths were considered to allow effective photothermal ablation of biological materials. The Free-Electron Laser (FEL) in Nieuwegein, NL (FELIX) is capable of delivering (far) IR laser light between 6 micrometers and 110 micrometers and was used for the first systematic investigation of the ablation quality (ablation depth per pulse and collateral damage beyond the surface) in the wavelength range between 12 micrometers and 70 micrometers . Porcine cadaver corneas were used as target material. Ablation depth per pulse as well as collateral thermal damage (extension of eosinophilic zone beyond the irradiated surface) were measured by histologic micrometry. It was found that the applied IR laser light can be used for an effective ablation of biological materials with a high water content. The experimental data are compared with theoretical values according to a previously described model for photoablation.

Citation Download Citation

Rudolf Walker, Manfred Ostertag, Thomas Bende, P. Wim van Amersfoort, and Benedikt J. Jean M.D. "Photoablation with the free-electron laser in the far IR in biological soft tissue (cornea)", Proc. SPIE 2391, Laser-Tissue Interaction VI, (22 May 1995); https://doi.org/10.1117/12.209875

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
12 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Laser ablation

Absorption

Cornea

Free electron lasers

Far infrared

Laser tissue interaction

Mirrors

Show All Keywords

Keywords/Phrases

Search In:

Publication Years