Calibration systems for surface plasmon resonance spectroscopy

Marc Kenneth Boysworth; Louis A. Obando; Karl S. Booksh

doi:10.1117/12.371305

23 November 1999 Calibration systems for surface plasmon resonance spectroscopy

Marc Kenneth Boysworth, Louis A. Obando, Karl S. Booksh

Proceedings Volume 3856, Internal Standardization and Calibration Architectures for Chemical Sensors; (1999) https://doi.org/10.1117/12.371305
Event: Photonics East '99, 1999, Boston, MA, United States

Abstract

Novel, field portable, inexpensive, easy to fabricate, optical fiber waveguide Surface Plasmon Resonance (SPR) sensors have been developed. Such sensors show exceptional promise in process and environmental monitoring. These sensors generate SPR features that are broader than prism- based SPR features. While these wide features are troublesome to calibrate using the univariate method traditional to SPR, multivariate methods of calibration have been applied to these new SPR sensors. Multivariate calibration has shown a fifty-percent improvement in predictive accuracy compared to univariate methods. In select case, the multivariate calibrations have been an order of magnitude better than the univariate methods. Traditional and new calibration methods for SPR are discussed, and recommendations are made regarding choice of regression modes, data density, and calibration set makeup for calibration of SPR using novel optical fiber waveguide SPR.

Citation Download Citation

Marc Kenneth Boysworth, Louis A. Obando, and Karl S. Booksh "Calibration systems for surface plasmon resonance spectroscopy", Proc. SPIE 3856, Internal Standardization and Calibration Architectures for Chemical Sensors, (23 November 1999); https://doi.org/10.1117/12.371305

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available