Pilot study: intravenous use of indocyanine green as an enhancer for 808-nm diode laser application in the equine

Lloyd P. Tate V.D.M.; Anthony T. Blikslager; Mark G. Papich

doi:10.1117/12.386286

17 May 2000 Pilot study: intravenous use of indocyanine green as an enhancer for 808-nm diode laser application in the equine

Lloyd P. Tate V.D.M., Anthony T. Blikslager, Mark G. Papich

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Proceedings Volume 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X; (2000) https://doi.org/10.1117/12.386286
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

The 808-nm diode laser, delivering 20 - 40 watts of power, has been produced for medical applications by several manufacturers over the past 10 years. This laser's power output is less than most Neodymium:yttrium aluminum garnet (Nd:YAG) lasers and other high power cutting lasers that use fiberoptic delivery systems. The 808-nm diode laser has not gained popularity in equine transendoscopic laser surgery. Indocyanine green (ICG) is absorbed at 810-nm of light which when concentrated in tissue should be an excellent absorber for the energy produced by the 808-nm diode laser. This study compares the depths and widths of penetration achieved with the 808-nm diode laser after intravenous injection of ICG in equine respiratory tissue. Indocyanine green was administered at two doses: 1.5 mg/kg and 3 mg/kg. The 808-nm diode laser was set to deliver 200 joules of energy. The depths and widths of penetration were also compared to the Nd:YAG laser applied at the same energy setting.

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Lloyd P. Tate V.D.M., Anthony T. Blikslager, and Mark G. Papich "Pilot study: intravenous use of indocyanine green as an enhancer for 808-nm diode laser application in the equine", Proc. SPIE 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X, (17 May 2000); https://doi.org/10.1117/12.386286

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KEYWORDS

Nd:YAG lasers

Semiconductor lasers

Laser tissue interaction

Indocyanine green

Laser therapeutics

Fiber lasers

Laser cutting

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