Light-scattering model for biological tissue

Shusen Xie; Hui Li; Lei Lin

doi:10.1117/12.388074

13 June 2000 Light-scattering model for biological tissue

Shusen Xie, Hui Li, Lei Lin

Proceedings Volume 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical; (2000) https://doi.org/10.1117/12.388074
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

We suggest that the optical model of a tissue is constructed by different size particles and the corresponding density in a liquid just like some phantoms of tissues. Due to the fact that the nonhomogeneous dimension is about the order of several and hundred micrometers, the Fraunhofer diffraction and process are applicable to biological tissue. We define n(r) as the number of particles per unit volume in tissue with radiuses between r and r + d r, i.e. n(r) is an unnormalized probability density function. We have verified that all of scattering properties of tissue can be obtained as long as the equivalent particle size distribution function n(r) is measured. In particular, the relation between (mu) _s and S((theta) ) is dependent on the n(r). The equivalent particle size distribution is feasible for experimental methods and techniques, as well as necessary for scattering principle. Furthermore, the equivalent particle size distribution provide not only a new understanding about the scattering properties of tissue but also a new approach to obtain the scattering coefficient and phase function. In addition, this scheme is helpful to design more precision tissue-simulating phantoms.

Citation Download Citation

Shusen Xie, Hui Li, and Lei Lin "Light-scattering model for biological tissue", Proc. SPIE 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical, (13 June 2000); https://doi.org/10.1117/12.388074

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
5 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Scattering

Particles

Tissue optics

Light scattering

Tissues

Refractive index

Mathematical modeling

Show All Keywords

Keywords/Phrases

Search In:

Publication Years