Biomicroscopic and speckle-interferometric measurement of lymph flow velocity in single microvessels in norm and in drug application

Ekateryna I. Galanzha

doi:10.1117/12.431559

4 May 2001 Biomicroscopic and speckle-interferometric measurement of lymph flow velocity in single microvessels in norm and in drug application

Ekateryna I. Galanzha

Author Affiliations +

Proceedings Volume 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II; (2001) https://doi.org/10.1117/12.431559
Event: Saratov Fall Meeting 2000, 2001, Saratov, Russian Federation

Abstract

In this paper we investigated the lymph flow and other parameters of lymph microcirculation in vivo. The analysis of lymphatic functions in norm and at the topical application of N-nitro-L-arginin (L-NNA, 10^-4M), dimethylsulfoxide (DMSO, 30%) was performed. We observed lymph microvessels of rat mesentery with diameter from 50 to 270 micrometers . The lymph flow velocity was determined by the biomicroscopic (V) and speckle-interferometrical (M₁) methods. L-NNA and DMSO led to different effects on diameters of lymphatics. L-NNA as well as DMSO stimulated the phasic activity and lymph flow in microvessels of rat mesentery. We suggested that used vasoactive drugs stimulated lymph pumping by different ways.

Citation Download Citation

Ekateryna I. Galanzha "Biomicroscopic and speckle-interferometric measurement of lymph flow velocity in single microvessels in norm and in drug application", Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); https://doi.org/10.1117/12.431559

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