Multiwavelet grading of prostate pathological images

Hamid Soltanian-Zadeh; Kourosh Jafari-Khouzani

doi:10.1117/12.467070

9 May 2002 Multiwavelet grading of prostate pathological images

Hamid Soltanian-Zadeh, Kourosh Jafari-Khouzani

Proceedings Volume 4684, Medical Imaging 2002: Image Processing; (2002) https://doi.org/10.1117/12.467070
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

We have developed image analysis methods to automatically grade pathological images of prostate. The proposed method generates Gleason grades to images, where each image is assigned a grade between 1 and 5. This is done using features extracted from multiwavelet transformations. We extract energy and entropy features from submatrices obtained in the decomposition. Next, we apply a k-NN classifier to grade the image. To find optimal multiwavelet basis, preprocessing, and classifier, we use features extracted by different multiwavelets with either critically sampled preprocessing or repeated row preprocessing and different k-NN classifiers and compare their performances, evaluated by total misclassification rate (TMR). To evaluate sensitivity to noise, we add white Gaussian noise to images and compare the results (TMR's). We applied proposed methods to 100 images. We evaluated the first and second levels of decomposition using Geronimo, Hardin, and Massopust (GHM), Chui and Lian (CL), and Shen (SA4) multiwavelets. We also evaluated k-NN classifier for k=1,2,3,4,5. Experimental results illustrate that first level of decomposition is quite noisy. They also show that critically sampled preprocessing outperforms repeated row preprocessing and has less sensitivity to noise. Finally, comparison studies indicate that SA4 multiwavelet and k-NN classifier (k=1) generates optimal results (with smallest TMR of 3%).

Citation Download Citation

Hamid Soltanian-Zadeh and Kourosh Jafari-Khouzani "Multiwavelet grading of prostate pathological images", Proc. SPIE 4684, Medical Imaging 2002: Image Processing, (9 May 2002); https://doi.org/10.1117/12.467070

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