In vitro glucose measurements using a two-wavelength CO2 laser

Juergen Lademann; Heike Richter; Martina Meinke; Gerhard J. Mueller; Pavel Kapustin; Victor I. Masychev; Yuri N. Bulkin; Klaus W. Berndt; Wolfram Sterry

doi:10.1117/12.485581

23 July 2003 In vitro glucose measurements using a two-wavelength CO₂ laser

Juergen Lademann, Heike Richter, Martina Meinke, Gerhard J. Mueller, Pavel Kapustin, Victor I. Masychev, Yuri N. Bulkin, Klaus W. Berndt, Wolfram Sterry

Author Affiliations +

Proceedings Volume 4965, Optical Diagnostics and Sensing in Biomedicine III; (2003) https://doi.org/10.1117/12.485581
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

A two wavelengths CO₂ laser was used to determine the glucose concentration in whole blood samples. For this purpose, the first laser wavelength λ₁ was tuned to the maximum of the glucose absorption band at 1080 cm^-1 and the second laser wavelength λ₂ was tuned to the background close to the glucose absorption band at 950 cm^-1. The difference of the laser power λ₁ and λ₂ behind the optical cell containing the whole blood sample was determined. This signal correlates strongly with the glucose concentration in the whole blood samples. The results of the investigation were compared to the results obtained by FTIR measurements.

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Juergen Lademann, Heike Richter, Martina Meinke, Gerhard J. Mueller, Pavel Kapustin, Victor I. Masychev, Yuri N. Bulkin, Klaus W. Berndt, and Wolfram Sterry "In vitro glucose measurements using a two-wavelength CO₂ laser", Proc. SPIE 4965, Optical Diagnostics and Sensing in Biomedicine III, (23 July 2003); https://doi.org/10.1117/12.485581

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