Differential thermal wave radiometry for noninvasive blood glucose monitoring: feasibility analysis

Sergey A. Telenkov

doi:10.1117/12.541944

12 April 2004 Differential thermal wave radiometry for noninvasive blood glucose monitoring: feasibility analysis

Sergey A. Telenkov

Proceedings Volume 5405, Thermosense XXVI; (2004) https://doi.org/10.1117/12.541944
Event: Defense and Security, 2004, Orlando, Florida, United States

Abstract

Blood glucose monitoring is essential for management of diabetes especially for those patients who requires regular insulin injections. A reliable noninvasive technique may eliminate inconvenience associated with frequent skin puncture to draw blood for measurement by a standard meter. Laser-induced thermal waves in tissue and detection of resulting IR response may provide a valuable approach to development of noninvasive glucose sensor. The present report analyzes radiometric response of tissue at the two wavelengths in mid-IR spectral band with phase-sensitive detection to evaluate feasibility of differential phase radiometry for noninvasive glucose monitoring. Sensitivity of the differential phase method is computed using two models of laser-tissue interaction: homogeneous light absorption and a discrete chromophore heating.

Citation Download Citation

Sergey A. Telenkov "Differential thermal wave radiometry for noninvasive blood glucose monitoring: feasibility analysis", Proc. SPIE 5405, Thermosense XXVI, (12 April 2004); https://doi.org/10.1117/12.541944

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