Accuracy of PCA-NN in non-invasively determining tissue optical properties from spatially resolved diffuse reflectance

Yaqin Chen; Ling Lin; Gang Li; Jianming Gao; Kaijie Wu

doi:10.1117/12.568730

18 January 2005 Accuracy of PCA-NN in non-invasively determining tissue optical properties from spatially resolved diffuse reflectance

Yaqin Chen, Ling Lin, Gang Li, Jianming Gao, Kaijie Wu

Author Affiliations +

Proceedings Volume 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II; (2005) https://doi.org/10.1117/12.568730
Event: Photonics Asia, 2004, Beijing, China

Abstract

In this paper, with reference to practical applications, we investigate the accuracy of the PCA-NN method in determining the optical properties μ_a and μ_s' from the spatially resolved relative reflectance data produced by Monte Carlo simulations. To test prediction performance of PCA-NN from the reflectance data with different lengths and different measurement noises, we constructed six PCA-NNs respectively corresponding to data length = 5, 10, 15, 20, 25 and 30 mm, which were trained by higher precision reflectance produced with photons = 10⁷. Then lower precision reflectance generated with photons = 10⁴, 2 × 10⁴, 5 × 10⁴, 7 × 10⁴, 10⁵, 2 × 10⁵, 5 × 10⁵, 7 × 10⁵ and 10⁶ were inputted to PCA-NNs to extract μ_a and μ_s' and the accuracy of μ_a and μ_s' was calculated, respectively. The results showed that for the reflectance with the same data length, the prediction errors of μ_a and μ_s' increase as the data noise increases; but for the reflectance with the same data precision, the errors decrease as the data length becomes longer. In conclusion, the preliminary results in this paper provide a guideline for choosing appropriate measurement conditions or estimating the prediction errors in reality.

Citation Download Citation

Yaqin Chen, Ling Lin, Gang Li, Jianming Gao, and Kaijie Wu "Accuracy of PCA-NN in non-invasively determining tissue optical properties from spatially resolved diffuse reflectance", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); https://doi.org/10.1117/12.568730

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KEYWORDS

Reflectivity

Monte Carlo methods

Photons

Optical properties

Signal to noise ratio

Diffuse reflectance spectroscopy

Tissue optics

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