Clinical feasibility of various optical instruments for quantitative evaluation of pulsed-dye laser treatment of port wine stain skin

Chang-Seok Kim; Byungjo Jung; Bernard Choi; Wim Verkruysse; Rong Zhang; John Stuart Nelson

doi:10.1117/12.589706

25 April 2005 Clinical feasibility of various optical instruments for quantitative evaluation of pulsed-dye laser treatment of port wine stain skin

Chang-Seok Kim, Byungjo Jung, Bernard Choi, Wim Verkruysse, Rong Zhang, John Stuart Nelson

Author Affiliations +

Proceedings Volume 5686, Photonic Therapeutics and Diagnostics; (2005) https://doi.org/10.1117/12.589706
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

For quantitative prediction and evaluation of pulsed dye laser therapy of port wine stain (PWS) skin, the CIE L*a*b* color difference, ΔE*, has been utilized to characterize numerically the color differences between normal untreated and treated PWS skin. Three optical instruments (Minolta chromameter CR-200, a cross-polarized diffuse reflectance imaging system, and visual reflectance spectrometers) are compared to investigate their clinical feasibility for quantitative color assessment. Compared to the chromameter as a standard measurement instrument, other instruments also provide valuable measurements of skin color for the relative quantification of PWS treatment outcome. The fiber-optic visual reflectance spectrometer is preferable for continuous measurement of a small area of skin. The cross-polarized imaging system is useful as a simple non-contact measurement technique to provide spatially resolved color difference images.

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Chang-Seok Kim, Byungjo Jung, Bernard Choi, Wim Verkruysse, Rong Zhang, and John Stuart Nelson "Clinical feasibility of various optical instruments for quantitative evaluation of pulsed-dye laser treatment of port wine stain skin", Proc. SPIE 5686, Photonic Therapeutics and Diagnostics, (25 April 2005); https://doi.org/10.1117/12.589706

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