Clinical studies using ultrahigh resolution and high-speed optical coherence tomography

Maciej Wojtkowski; Vivek Jay Srinivasan; Tony Hong-Tyng Ko; James G. Fujimoto; Jay S. Duker; Annie Chan; Joel S. Schuman; Andrzej Kowalczyk

doi:10.1117/12.591092

18 April 2005 Clinical studies using ultrahigh resolution and high-speed optical coherence tomography

Maciej Wojtkowski, Vivek Jay Srinivasan, Tony Hong-Tyng Ko, James G. Fujimoto, Jay S. Duker, Annie Chan, Joel S. Schuman, Andrzej Kowalczyk

Author Affiliations +

Proceedings Volume 5688, Ophthalmic Technologies XV; (2005) https://doi.org/10.1117/12.591092
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

We present clinical data obtained with the aid of a novel instrumentation using, high speed, ultrahigh resolution Spectral/Fourier domain Optical Coherence Tomography (SOCT). This method allows performing video rate, ultrahigh resolution cross-sectional images with 98 dB of sensitivity, 100 times faster that previously reported UHR OCT system with comparable axial resolution of 3 um. Ultrahigh resolution imaging enables improved visualization of retinal architectural morphology compared to standard resolution OCT. High speed, ultrahigh resolution OCT using Spectral/Fourier domain detection promises to significantly enhance the utility of OCT for clinical applications. High speed imaging enables high density data sets to be acquired which can increase the quality of reconstructed cross-sectional images and can help to visualize small focal pathologic changes. This technique helps reconstructing true retinal topography without motion artifacts. Submitted manuscript describes the technology, its clinical performance and present preliminary data obtained for various retinal pathologies.

Citation Download Citation

Maciej Wojtkowski, Vivek Jay Srinivasan, Tony Hong-Tyng Ko, James G. Fujimoto, Jay S. Duker, Annie Chan, Joel S. Schuman, and Andrzej Kowalczyk "Clinical studies using ultrahigh resolution and high-speed optical coherence tomography", Proc. SPIE 5688, Ophthalmic Technologies XV, (18 April 2005); https://doi.org/10.1117/12.591092

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