From lab-on-a-chip to lab-in-a-cell

Helene Andersson; Albert van den Berg

doi:10.1117/12.601553

22 January 2005 From lab-on-a-chip to lab-in-a-cell

Helene Andersson, Albert van den Berg

Proceedings Volume 5718, Microfluidics, BioMEMS, and Medical Microsystems III; (2005) https://doi.org/10.1117/12.601553
Event: MOEMS-MEMS Micro and Nanofabrication, 2005, San Jose, California, United States

Abstract

There are many efforts today trying to mimic the properties of single cells in order to design chips that are as efficient as cells. However, cells are nature’s nanotechnology engineering at the scale of atoms and molecules. Therefore, it might be better to vision a microchip that utilizes a single cell as experimentation platform. A novel, so-called Lab-in-a-Cell (LIC) concept is described, where advantage is taken of micro/nanotechnological tools to enable precise control of the biochemical cellular environment and possibility to analyze the composition of single cells. This is followed by a review on the present chip solutions for single cell handling and analysis.

Citation Download Citation

Helene Andersson and Albert van den Berg "From lab-on-a-chip to lab-in-a-cell", Proc. SPIE 5718, Microfluidics, BioMEMS, and Medical Microsystems III, (22 January 2005); https://doi.org/10.1117/12.601553

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