Shortest path adjusted similarity metrics for resolving boundary perturbations in scaffold images for tissue engineering

Srinivasan Rajagopalan; Richard Robb

doi:10.1117/12.654000

15 March 2006 Shortest path adjusted similarity metrics for resolving boundary perturbations in scaffold images for tissue engineering

Srinivasan Rajagopalan, Richard Robb

Author Affiliations +

Proceedings Volume 6144, Medical Imaging 2006: Image Processing; 61444E (2006) https://doi.org/10.1117/12.654000
Event: Medical Imaging, 2006, San Diego, California, United States

Abstract

The degree of match between the delineation result produced by a segmentation technique and the ground truth can be assessed using robust "presence-absence" resemblance measures. Previously, we had investigated and introduced an exhaustive list of similarity indices for assessing multiple segmentation techniques. However, these measures are highly sensitive to even minor boundary perturbations which imminently manifest in the segmentations of random biphasic spaces reminiscent of the stochastic pore-solid distributions in the tissue engineering scaffolds. This paper investigates the ideas adapted from ecology to emphasize global resemblances and ignore minor local dissimilarities. It uses concepts from graph theory to perform controlled local mutations in order to maximize the similarities. The effect of this adjustment is investigated on a comprehensive list (forty nine) of similarity indices sensitive to the over- and under- estimation errors associated with image delineation tasks.

Citation Download Citation

Srinivasan Rajagopalan and Richard Robb "Shortest path adjusted similarity metrics for resolving boundary perturbations in scaffold images for tissue engineering", Proc. SPIE 6144, Medical Imaging 2006: Image Processing, 61444E (15 March 2006); https://doi.org/10.1117/12.654000

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available