Theoretical and experimental study on near infrared time-resolved optical diffuse tomography

Huijuan Zhao; Feng Gao; Yukari Tanikawa; Yukio Yamada

doi:10.1117/12.696958

21 July 2006 Theoretical and experimental study on near infrared time-resolved optical diffuse tomography

Huijuan Zhao, Feng Gao, Yukari Tanikawa, Yukio Yamada

Proceedings Volume 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII; 61630G (2006) https://doi.org/10.1117/12.696958
Event: Saratov Fall Meeting 2005, 2005, Saratov, Russian Federation

Abstract

Parts of the works of our group in the past five years on near infrared time-resolved (TR) optical tomography are summarized in this paper. The image reconstruction algorithm is based on Newton Raphson scheme with a datatype R generated from modified Generalized Pulse Spectrum Technique. Firstly, the algorithm is evaluated with simulated data from a 2-D model and the datatype R is compared with other popularly used datatypes. In this second part of the paper, the in vitro and in vivo NIR DOT imaging on a chicken leg and a human forearm, respectively are presented for evaluating both the image reconstruction algorithm and the TR measurement system. The third part of this paper is about the differential pathlength factor of human head while monitoring head activity with NIRS and applying the modified Lambert-Beer law. Benefiting from the TR system, the measured DPF maps of the three import areas of human head are presented in this paper.

Citation Download Citation

Huijuan Zhao, Feng Gao, Yukari Tanikawa, and Yukio Yamada "Theoretical and experimental study on near infrared time-resolved optical diffuse tomography", Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61630G (21 July 2006); https://doi.org/10.1117/12.696958

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