A new scheme for time-resolved diffusing wave spectroscopy

Katarzyna Zarychta; Hà Liên Nghiêm; Monia Cheikh; Eric Tinet; Sigrid Avrillier; Jean-Michel Tualle

doi:10.1117/12.696004

15 September 2006 A new scheme for time-resolved diffusing wave spectroscopy

Katarzyna Zarychta, Hà Liên Nghiêm, Monia Cheikh, Eric Tinet, Sigrid Avrillier, Jean-Michel Tualle

Proceedings Volume 6341, Speckle06: Speckles, From Grains to Flowers; 634132 (2006) https://doi.org/10.1117/12.696004
Event: Speckle06: Speckles, From Grains to Flowers, 2006, Nimes, France

Abstract

Diffusing Wave Spectroscopy (DWS) consists in the measurement of temporal correlation of the electromagnetic field in the diffusion regime, allowing a scan of dynamical properties deep inside a medium. DWS is of special interest in biomedical optics, as it is sensitive to blood circulation in capillaries inside the tissue. However one main difficulty of this technique concerns data extraction which implies to perform an inverse problem taking into account the geometry and the optical coefficients of the medium. The use of time-resolved detection has been proved to be an efficient tool to discriminate the DWS information, but the photon path lengths were up to now limited to a few tens mean free paths. In order to perform time-resolved DWS for much longer photon paths, we used a new method, based on the use of an interferometer and a wavelength modulated source. We have already demonstrated that this method, in addition to its lower cost, was very efficient to perform time-resolved measurements of the light scattered by a thick scattering medium. We will show in this poster some measurements performed by transillumination through a thick medium (4cm), opening the possibility of Time-Resolved DWS measurements in the human breast.

Citation Download Citation

Katarzyna Zarychta, Hà Liên Nghiêm, Monia Cheikh, Eric Tinet, Sigrid Avrillier, and Jean-Michel Tualle "A new scheme for time-resolved diffusing wave spectroscopy", Proc. SPIE 6341, Speckle06: Speckles, From Grains to Flowers, 634132 (15 September 2006); https://doi.org/10.1117/12.696004

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KEYWORDS

Modulation

Spectroscopy

Spatial resolution

Transmittance

Diffusion

Light scattering

Optical testing

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