Birefringence imaging of biological tissue by spectral domain polarization sensitive optical coherence tomography

Zhijun Jing; Chuanmao Fan; Jingying Jiang; Qiang Gong; Zhenhe Ma; Fan Zhang; Jianquan Yao; R. K. Wang

doi:10.1117/12.705736

7 February 2007 Birefringence imaging of biological tissue by spectral domain polarization sensitive optical coherence tomography

Zhijun Jing, Chuanmao Fan, Jingying Jiang, Qiang Gong, Zhenhe Ma, Fan Zhang, Jianquan Yao, R. K. Wang

Author Affiliations +

Proceedings Volume 6439, Optics in Tissue Engineering and Regenerative Medicine; 64390J (2007) https://doi.org/10.1117/12.705736
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

A spectral domain Polarization sensitive optical coherence tomography (SDPS-OCT) system has been developed to acquire depth images of biological tissues such as porcine tendon, rabbit eye. The Stocks vectors (I, Q, U, and V) of the backscattered light from the biological tissues have been reconstructed. Further, the phase retardation and polarization degree between the two orthogonal polarizing states have been computed. Reconstructed images, i.e. birefringence images, from Stokes parameters, retardation and polarization degree of biological tissues show significant local variations in the polarization state. And the birefringence contrast of biological tissue possibly changes by some outside force. In addition, the local thickness of the birefringence layer determined with our system is significant. The results presented show SDPS-OCT is a potentially powerful technique to investigate tissue structural properties on the basis of the fact that any fibrous structure with biological tissues can influence the polarization state of light.

Citation Download Citation

Zhijun Jing, Chuanmao Fan, Jingying Jiang, Qiang Gong, Zhenhe Ma, Fan Zhang, Jianquan Yao, and R. K. Wang "Birefringence imaging of biological tissue by spectral domain polarization sensitive optical coherence tomography", Proc. SPIE 6439, Optics in Tissue Engineering and Regenerative Medicine, 64390J (7 February 2007); https://doi.org/10.1117/12.705736

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available