The VU-DBS project: integrated and computer-assisted planning, intra-operative placement, and post-operative programming of deep-brain stimulators

Benoit M. Dawant; Pierre-Francois D'Haese; Srivatsan Pallavaram; Rui Li; Hong Yu; John Spooner; Thomas Davis; Chris Kao; Peter E Konrad

doi:10.1117/12.711149

21 March 2007 The VU-DBS project: integrated and computer-assisted planning, intra-operative placement, and post-operative programming of deep-brain stimulators

Benoit M. Dawant, Pierre-Francois D'Haese, Srivatsan Pallavaram, Rui Li, Hong Yu, John Spooner, Thomas Davis, Chris Kao, Peter E Konrad

Author Affiliations +

Proceedings Volume 6509, Medical Imaging 2007: Visualization and Image-Guided Procedures; 650907 (2007) https://doi.org/10.1117/12.711149
Event: Medical Imaging, 2007, San Diego, CA, United States

Abstract

Movement disorders affect over 5,000,000 people in the United States. Contemporary treatment of these diseases involves high-frequency stimulation through deep brain stimulation (DBS). This form of therapy is offered to patients who have begun to see failure with standard medical therapy and also to patients for which medical therapy is poorly effective. A DBS procedure involves the surgical placement, with millimetric accuracy, of an electrode in the proximity of functional areas referred to as targets. Following the surgical procedure, the implant, which is a multi-contact electrode is programmed to alleviate symptoms while minimizing side effects. Surgical placement of the electrode is difficult because targets of interest are poorly visible in current imaging modalities. Consequently, the process of implantation of a DBS electrode is an iterative procedure. An approximate target position is determined pre-operatively from the position of adjacent structures that are visible in MR images. With the patient awake, this position is then adjusted intra-operatively, which is a lengthy process. The post-surgical programming of the stimulator is an equally challenging and time consuming task, with parameter setting combinations exceeding 4000. This paper reports on the status of the Vanderbilt University DBS Project, which involves the development and clinical evaluation of a system designed to facilitate the entire process from the time of planning to the time of programming.

Citation Download Citation

Benoit M. Dawant, Pierre-Francois D'Haese, Srivatsan Pallavaram, Rui Li, Hong Yu, John Spooner, Thomas Davis, Chris Kao, and Peter E Konrad "The VU-DBS project: integrated and computer-assisted planning, intra-operative placement, and post-operative programming of deep-brain stimulators", Proc. SPIE 6509, Medical Imaging 2007: Visualization and Image-Guided Procedures, 650907 (21 March 2007); https://doi.org/10.1117/12.711149

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available