Toward computer-aided emphysema quantification on ultralow-dose CT: reproducibility of ventrodorsal gravity effect measurement and correction

Rafael Wiemker; Roland Opfer; Thomas Bülow; Patrik Rogalla; Amnon Steinberg; Ekta Dharaiya; Krishna Subramanyan

doi:10.1117/12.705868

29 March 2007 Toward computer-aided emphysema quantification on ultralow-dose CT: reproducibility of ventrodorsal gravity effect measurement and correction

Rafael Wiemker, Roland Opfer, Thomas Bülow, Patrik Rogalla, Amnon Steinberg, Ekta Dharaiya, Krishna Subramanyan

Author Affiliations +

Proceedings Volume 6514, Medical Imaging 2007: Computer-Aided Diagnosis; 65140O (2007) https://doi.org/10.1117/12.705868
Event: Medical Imaging, 2007, San Diego, CA, United States

Abstract

Computer aided quantification of emphysema in high resolution CT data is based on identifying low attenuation areas below clinically determined Hounsfield thresholds. However, the emphysema quantification is prone to error since a gravity effect can influence the mean attenuation of healthy lung parenchyma up to ± 50 HU between ventral and dorsal lung areas. Comparing ultra-low-dose (7 mAs) and standard-dose (70 mAs) CT scans of each patient we show that measurement of the ventrodorsal gravity effect is patient specific but reproducible. It can be measured and corrected in an unsupervised way using robust fitting of a linear function.

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Rafael Wiemker, Roland Opfer, Thomas Bülow, Patrik Rogalla, Amnon Steinberg, Ekta Dharaiya, and Krishna Subramanyan "Toward computer-aided emphysema quantification on ultralow-dose CT: reproducibility of ventrodorsal gravity effect measurement and correction", Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 65140O (29 March 2007); https://doi.org/10.1117/12.705868

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