Respiratory-gated micro-CT using a carbon nanotube based micro-focus field emission x-ray source

Guohua Cao; Yueh Z. Lee; Zejian Liu; Ramya Rajaram; Rui Peng; Xiomara Calderon-Colon; Lei An; Peng Wang; Tuyen Phan; David Lalush; Jianping Lu; Otto Zhou

doi:10.1117/12.770592

18 March 2008 Respiratory-gated micro-CT using a carbon nanotube based micro-focus field emission x-ray source

Guohua Cao, Yueh Z. Lee, Zejian Liu, Ramya Rajaram, Rui Peng, Xiomara Calderon-Colon, Lei An, Peng Wang, Tuyen Phan, David Lalush, Jianping Lu, Otto Zhou

Author Affiliations +

Proceedings Volume 6913, Medical Imaging 2008: Physics of Medical Imaging; 691304 (2008) https://doi.org/10.1117/12.770592
Event: Medical Imaging, 2008, San Diego, California, United States

Abstract

A prototype physiologically gated micro-computed tomography (micro-CT) system based on a field emission micro-focus x-ray source has been developed for in vivo imaging of small animal models. The novel x-ray source can generate radiation with a programmable waveform that can be readily synchronized and gated with non-periodic physiological signals. The system performance is evaluated using phantoms and sacrificed and anesthetized mouse models. Prospective respiratory-gated CT images of anesthetized free-breathing mice are collected using this scanner at 100msec temporal resolution and 10 lp/mm of 10% system MTF.

Citation Download Citation

Guohua Cao, Yueh Z. Lee, Zejian Liu, Ramya Rajaram, Rui Peng, Xiomara Calderon-Colon, Lei An, Peng Wang, Tuyen Phan, David Lalush, Jianping Lu, and Otto Zhou "Respiratory-gated micro-CT using a carbon nanotube based micro-focus field emission x-ray source", Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 691304 (18 March 2008); https://doi.org/10.1117/12.770592

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