Reduction of background in optoacoustic image sequences obtained under tissue deformation

Michael Jaeger; Lea Siegenthaler; Michael Kitz; Martin Frenz

doi:10.1117/12.810074

12 February 2009 Reduction of background in optoacoustic image sequences obtained under tissue deformation

Michael Jaeger, Lea Siegenthaler, Michael Kitz, Martin Frenz

Proceedings Volume 7177, Photons Plus Ultrasound: Imaging and Sensing 2009; 71770Z (2009) https://doi.org/10.1117/12.810074
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

For real-time optoacoustic imaging of the human body, a linear array transducer and reflection mode optical irradiation is preferably used. Experimental outcomes however revealed that such a setup results in significant image background, which prevents imaging structures at the ultimate depth limited only by optical attenuation and the signal noise level. Various sources of image background such as bulk tissue absorption, reconstruction artifacts, and backscattered ultrasound could be identified. We therefore developed a novel method which results in significantly reduced background and increased imaging depth. For this purpose, we acquire in parallel a series of optoacoustic and echo-ultrasound images while the tissue sample is gradually deformed by an externally applied force. Optoacoustic signals and background signals are differently affected by the deformation and can thus be distinguished by image processing. This method takes advantage of a combined optoacoustic/echo-ultrasound device and has a strong potential for improving real-time optoacoustic imaging of deep tissue structures.

Citation Download Citation

Michael Jaeger, Lea Siegenthaler, Michael Kitz, and Martin Frenz "Reduction of background in optoacoustic image sequences obtained under tissue deformation", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770Z (12 February 2009); https://doi.org/10.1117/12.810074

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