Paper
6 March 2009 Photorejuvenation observation based on two photon microscopy
Shu-lian Wu, Hui Li, Zheng-ying Xiao, Shu-sen Xie
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Abstract
With low risk of complications and little down-time, the non-ablative photo-rejuvenation is playing an increasing role in the therapy of the photo-damaged skin, but the appraisal standard is different. This paper mainly observed the effect of the mouse skin irradiated by intense pulse light source through two photo microscopy in sub-micrometer. The spectrum and morphological imaging between pre- and post-irradiated by Intense Pulse Light (IPL) were obtained from two photon microscopy respectively. The outcome showed that non-ablative IPL irradiated the aging mouse skin got the better effect, and then have gained the changes of spectrum intensity and corresponding photon numbers in a rectangular area, these probable achieve the mechanism of light irradiated skin. The intention of this was offer the theory basis in clinic.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Shu-lian Wu, Hui Li, Zheng-ying Xiao, and Shu-sen Xie "Photorejuvenation observation based on two photon microscopy", Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 728022 (6 March 2009); https://doi.org/10.1117/12.821105
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KEYWORDS
Skin

Collagen

Two photon excitation microscopy

Second-harmonic generation

Signal detection

Optical filters

Sensors

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