Theoretical prediction for cell deformation in the optical traps

Paul B. Bareil; Yunlong Sheng; Arthur E. Chiou

doi:10.1117/12.826638

20 August 2009 Theoretical prediction for cell deformation in the optical traps

Paul B. Bareil, Yunlong Sheng, Arthur E. Chiou

Proceedings Volume 7400, Optical Trapping and Optical Micromanipulation VI; 74000D (2009) https://doi.org/10.1117/12.826638
Event: SPIE NanoScience + Engineering, 2009, San Diego, California, United States

Abstract

We present optical and mechanical models for cell's deformation in the optical traps. The morphological deformation of the cell is calculated from the local stress distribution on the cell using the linear theory of thin elastic membrane, which is valid for the cells without internal cytoskeletal structure, such as the red blood cells. This generic approach allows computing for a variety of experimental configurations and predicting cell's deformation. Comparison of the results with numerical calculation tool such as Mie scattering and T-Matrix is made. The coupling coefficient from one fiber to another through the deformed trapped cell in the fiber-optical dual-beam stretcher was calculated for fast monitoring of the cell deformation.

Citation Download Citation

Paul B. Bareil, Yunlong Sheng, and Arthur E. Chiou "Theoretical prediction for cell deformation in the optical traps", Proc. SPIE 7400, Optical Trapping and Optical Micromanipulation VI, 74000D (20 August 2009); https://doi.org/10.1117/12.826638

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