Surface plasmon resonance optical sensing for simultaneous multi-channel biological monitoring

Wei Peng; Soame Banerji; Yoon-Chang Kim; Karl S. Booksh

doi:10.1117/12.837291

25 November 2009 Surface plasmon resonance optical sensing for simultaneous multi-channel biological monitoring

Wei Peng, Soame Banerji, Yoon-Chang Kim, Karl S. Booksh

Proceedings Volume 7506, 2009 International Conference on Optical Instruments and Technology: Optical Systems and Modern Optoelectronic Instruments; 750613 (2009) https://doi.org/10.1117/12.837291
Event: International Conference on Optical Instrumentation and Technology, 2009, Shanghai, China

Abstract

This paper presents a multi-angle optical analysis device based on surface plasmon resonance (SPR) for simultaneous biological sample detection. Most applications of optical SPR devices were designed to measure refractive index (RI) of liquid or gas sample by measuring the signal wavelength or angle, the sensitivity and stability of which is easily affected by the fluctuation of various interior or exterior test conditions. In this study, we have proposed a multi-channel optical SPR device which can monitor SPR changes at different wavelengths and angles. The preliminary experimental results demonstrate the characteristic responses of SPR signals from different angles changes independently correspond to the refraction index changes of the liquid samples with which they are in contact. The experimental results confirmed that a practicable high-sensitivity multi-channel SPR biological measurement instrument could be completed with further developments.

Citation Download Citation

Wei Peng, Soame Banerji, Yoon-Chang Kim, and Karl S. Booksh "Surface plasmon resonance optical sensing for simultaneous multi-channel biological monitoring", Proc. SPIE 7506, 2009 International Conference on Optical Instruments and Technology: Optical Systems and Modern Optoelectronic Instruments, 750613 (25 November 2009); https://doi.org/10.1117/12.837291

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available