Terahertz pulsed imaging in vivo

E. Pickwell-MacPherson

doi:10.1117/12.871927

17 February 2011 Terahertz pulsed imaging in vivo

E. Pickwell-MacPherson

Proceedings Volume 7897, Optical Interactions with Tissue and Cells XXII; 78970C (2011) https://doi.org/10.1117/12.871927
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

Terahertz (10¹² Hz) pulsed imaging is a totally non-destructive and non-ionising imaging modality and thus potential applications in medicine are being investigated. In this paper we present results using our hand-held terahertz probe that has been designed for in vivo use. In particular, we use the terahertz probe to perform reflection geometry in vivo measurements of human skin. The hand-held terahertz probe gives more flexibility than a typical flat-bed imaging system, but it also results in noisier data and requires existing processing methods to be improved. We describe the requirements and limitations of system geometry, data acquisition rate, image resolution and penetration depth and explain how various factors are dependent on each other. We show how some of the physical limitations can be overcome using novel data processing methods.

Citation Download Citation

E. Pickwell-MacPherson "Terahertz pulsed imaging in vivo", Proc. SPIE 7897, Optical Interactions with Tissue and Cells XXII, 78970C (17 February 2011); https://doi.org/10.1117/12.871927

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