Multiple-illumination photoacoustic tomography: reconstructing absorption, scattering, and Grüeneisen coefficient distributions

Peng Shao; Ben Cox; Roger J. Zemp

doi:10.1117/12.875728

22 February 2011 Multiple-illumination photoacoustic tomography: reconstructing absorption, scattering, and Grüeneisen coefficient distributions

Peng Shao, Ben Cox, Roger J. Zemp

Author Affiliations +

Proceedings Volume 7899, Photons Plus Ultrasound: Imaging and Sensing 2011; 78993Z (2011) https://doi.org/10.1117/12.875728
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

Photoacoustic imaging is a promising technique combining high ultrasonic resolution and high optical contrast. However, quantification has proved rather challenging. In this paper, we present a non-iterative reconstruction strategy with multiple-optical-sources for reconstruction of absorption, scattering perturbations as well as the spatially varying Grüeneisen parameter from a known turbid background. We term this method the multiple-illumination photoacoustic tomography (MI-PAT). While numerical challenges still exist, we demonstrated that the linearized MI-PAT framework we propose has orders of magnitude improved condition number compared with Continuous-Wave Diffuse Optical Tomography (CW-DOT).

Citation Download Citation

Peng Shao, Ben Cox, and Roger J. Zemp "Multiple-illumination photoacoustic tomography: reconstructing absorption, scattering, and Grüeneisen coefficient distributions", Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 78993Z (22 February 2011); https://doi.org/10.1117/12.875728

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