Turbulence intensity in a region of interest 2cm distal to the carotid bifurcation in a family of seven anthropomorphic flow phantoms

Janet L. Powell; Tamie L. Poepping

doi:10.1117/12.878775

25 March 2011 Turbulence intensity in a region of interest 2cm distal to the carotid bifurcation in a family of seven anthropomorphic flow phantoms

Janet L. Powell, Tamie L. Poepping

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Proceedings Volume 7968, Medical Imaging 2011: Ultrasonic Imaging, Tomography, and Therapy; 796810 (2011) https://doi.org/10.1117/12.878775
Event: SPIE Medical Imaging, 2011, Lake Buena Vista (Orlando), Florida, United States

Abstract

An in vitro flow system has been used to assess the flow disturbances downstream of the stenosis in a family of seven carotid bifurcation phantoms modelling varying plaque build-up both axially symmetrically (concentrically) and asymmetrically (eccentrically). Radio frequency data were collected for 10 s at each of over 1000 sites within each model, and a sliding 1024-point FFT is applied to the data to extract the Doppler spectrum every 12 ms. From this, the ensemble average over 10 cardiac cycles of the spectral mean velocity, and the root mean square over these same 10 cardiac cycles - the turbulence intensity (TI), can be obtained as a function of an ensemble averaged cardiac cycle at each spatial point in all phantoms. TI was investigated by looking at the average over a 25 mm² square region of interest in the ICA centered 2 cm distal to the apex of the bifurcation. TI in the region of interest increased with stenosis severity; at 23ms following peak systole, the time point when TI was maximal for the majority of models, this ranged from 2.4±0.1 cm/s in the non-diseased model to 6.6±0.3, 16.0±1.4 and 26.1±1.3 cm/s in the 30, 50 and 70% concentrically stenosed (by NASCET criteria) models, respectively. Similarly, TI was 8.3±0.7, 19.9±1.1, and 26.2±1.2 cm/s in the 30, 50 and 70% eccentrically stenosed models, respectively. Differences in TI between models, both in increasing stenosis severity and between eccentricities, were statistically different except between the 70% concentric and eccentric models.

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Janet L. Powell and Tamie L. Poepping "Turbulence intensity in a region of interest 2cm distal to the carotid bifurcation in a family of seven anthropomorphic flow phantoms", Proc. SPIE 7968, Medical Imaging 2011: Ultrasonic Imaging, Tomography, and Therapy, 796810 (25 March 2011); https://doi.org/10.1117/12.878775

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KEYWORDS

Independent component analysis

Turbulence

Data modeling

Statistical modeling

Simulation of CCA and DLA aggregates

Doppler effect

Ultrasonography

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