Applications of laser-accelerated particle beams for radiation therapy

C.-M. Ma; E. Fourkal; J. S. Li; I. Veltchev; W. Luo; J. J. Fan; T. Lin; A. Tafo

doi:10.1117/12.889371

25 May 2011 Applications of laser-accelerated particle beams for radiation therapy

C.-M. Ma, E. Fourkal, J. S. Li, I. Veltchev, W. Luo, J. J. Fan, T. Lin, A. Tafo

Proceedings Volume 8079, Laser Acceleration of Electrons, Protons, and Ions; and Medical Applications of Laser-Generated Secondary Sources of Radiation and Particles; 80791B (2011) https://doi.org/10.1117/12.889371
Event: SPIE Optics + Optoelectronics, 2011, Prague, Czech Republic

Abstract

Proton beams are more advantageous than high-energy photons and electrons for radiation therapy because of their finite penetrating range and the Bragg peak near the end of their range, which have been utilized to achieve better dose conformity to the treatment target allowing for dose escalation and/or hypofractionation to increase local tumor control, reduce normal tissue complications and/or treatment time/cost. Proton therapy employing conventional particle acceleration techniques is expensive because of the large accelerators and treatment gantries that require excessive space and shielding. Compact proton acceleration systems are being sought to improve the cost-effectiveness for proton therapy. This paper reviews the physics principles of laser-proton acceleration and the development of prototype laserproton therapy systems as a solution for widespread applications of advanced proton therapy. The system design, the major components and the special delivery techniques for energy and intensity modulation are discussed in detail for laser-accelerated proton therapy.

Citation Download Citation

C.-M. Ma, E. Fourkal, J. S. Li, I. Veltchev, W. Luo, J. J. Fan, T. Lin, and A. Tafo "Applications of laser-accelerated particle beams for radiation therapy", Proc. SPIE 8079, Laser Acceleration of Electrons, Protons, and Ions; and Medical Applications of Laser-Generated Secondary Sources of Radiation and Particles, 80791B (25 May 2011); https://doi.org/10.1117/12.889371

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