Fluence mapping inside the highly scattering medium using reflection mode acousto-optics

Altaf Hussain; Khalid Daoudi; Erwin Hondebrink; Wiendelt Steenbergen

doi:10.1117/12.2002383

4 March 2013 Fluence mapping inside the highly scattering medium using reflection mode acousto-optics

Altaf Hussain, Khalid Daoudi, Erwin Hondebrink, Wiendelt Steenbergen

Proceedings Volume 8581, Photons Plus Ultrasound: Imaging and Sensing 2013; 85810U (2013) https://doi.org/10.1117/12.2002383
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Optical excitation based imaging modalities, with aim to image structures deep inside the scattering medium, suffer from quantification problem. We propose a methodology to solve the problem of non-invasively mapping the fluence in optically heterogeneous medium without the need of prior knowledge of its optical properties. We present a theoretical model of our concept and provide proof of principle with Monte Carlo simulations. Simulation results show that it is possible to measure the local light fluence in highly scattering medium in absolute terms. Furthermore, we performed an experiment to validate the concept as a strategy to measure local fluence in relative manners. We used reflection mode acousto optics (AO) in our experiment, and showed that with this method we can measure local light fluence (in relative term) in highly scattering medium.

Citation Download Citation

Altaf Hussain, Khalid Daoudi, Erwin Hondebrink, and Wiendelt Steenbergen "Fluence mapping inside the highly scattering medium using reflection mode acousto-optics", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85810U (4 March 2013); https://doi.org/10.1117/12.2002383

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available