Control of optical transmittance of fat tissue slices at NIR photodynamic action mediated by indocyanine green

I. Yu. Yanina; V. A. Doubrovsky; V. V. Tuchin

doi:10.1117/12.2017672

26 February 2013 Control of optical transmittance of fat tissue slices at NIR photodynamic action mediated by indocyanine green

I. Yu. Yanina, V. A. Doubrovsky, V. V. Tuchin

Author Affiliations +

Proceedings Volume 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV; 86990C (2013) https://doi.org/10.1117/12.2017672
Event: Saratov Fall Meeting and Workshop on Laser Physics and Photonics 2012, 2012, Saratov, Russian Federation

Abstract

The changes in optical transmittance of human adipose cell layers sensitized by indocyanine green (ICG) as a result of photodynamic action were found and studied. It was revealed experimentally that due to the selective action of laser radiation on fat tissue sensitized by ICG the spatial distribution of its optical transmittance becomes more homogeneous. The statistical computer processing of digital images allowed one to estimate tissue optical transmittance, its spatial and temporal distributions. These quantitative estimations correlated well with the visible changes of tissue images. The measurements carried out gave an opportunity to suggest the interpretation of the phenomenon observed.

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I. Yu. Yanina, V. A. Doubrovsky, and V. V. Tuchin "Control of optical transmittance of fat tissue slices at NIR photodynamic action mediated by indocyanine green", Proc. SPIE 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV, 86990C (26 February 2013); https://doi.org/10.1117/12.2017672

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