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18 November 2013 Spatial measurement of spurious forces with optical tweezers
Ignacio Bordeu, Giovanni Volpe, Juan Pablo Staforelli
Author Affiliations +
Proceedings Volume 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications; 878509 (2013) https://doi.org/10.1117/12.2027533
Event: 8th Ibero American Optics Meeting/11th Latin American Meeting on Optics, Lasers, and Applications, 2013, Porto, Portugal
Abstract
The study of diffusion in a crowded and complex environment, such as inside a cell or within a porous medium, is of fundamental importance for science and technology. Combining blinking holographic optical tweezers and sub-pixel video microscopy permits one to study Brownian motion in confined geometries. In this work, in particular, we have studied the Brownian motion of two colloidal particles interacting hydrodynamically with each other. The proximity between the two microspheres induces a space-dependence in the particles diffusion coefficient and, therefore, a spurious drift. We measure this drift and evaluate the magnitude of the spurious force associated with it. We present the optoelectronic tools employed in the experiment and we discuss the experimental results.
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Ignacio Bordeu, Giovanni Volpe, and Juan Pablo Staforelli "Spatial measurement of spurious forces with optical tweezers", Proc. SPIE 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications, 878509 (18 November 2013); https://doi.org/10.1117/12.2027533
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KEYWORDS
Particles

Diffusion

Optical tweezers

Video

Holography

Stochastic processes

Data modeling

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