Low level laser therapy on injured rat muscle

M. Mantineo; J. P. Pinheiro; A. M. Morgado

doi:10.1117/12.2032496

24 June 2013 Low level laser therapy on injured rat muscle

M. Mantineo, J. P. Pinheiro, A. M. Morgado

Proceedings Volume 8803, Medical Laser Applications and Laser-Tissue Interactions VI; 88030E (2013) https://doi.org/10.1117/12.2032496
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

Although studies show the clinical effectiveness of low level laser therapy (LLLT) in facilitating the muscle healing process, scientific evidence is still required to prove the effectiveness of LLLT and to clarify the cellular and molecular mechanisms triggered by irradiation. Here we evaluate the effect of different LLLT doses, using continuous illumination (830 nm), in the treatment of inflammation induced in the gastrocnemius muscle of Wistar rats, through the quantification of cytokines in systemic blood and histological analysis of muscle tissue. We verified that all applied doses produce an effect on reducing the number of inflammatory cells and the concentration of pro-inflammatory TNF-α and IL-1β cytokines. The best results were obtained for 40 mW. The results may suggest a biphasic dose response curve.

Citation Download Citation

M. Mantineo, J. P. Pinheiro, and A. M. Morgado "Low level laser therapy on injured rat muscle", Proc. SPIE 8803, Medical Laser Applications and Laser-Tissue Interactions VI, 88030E (24 June 2013); https://doi.org/10.1117/12.2032496

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