Optical fibre cantilever sensor for biological application

J. Li; Y. X. Zhou; G. Patterson; W. M. Shu; R. R. J. Maier; R. Fowler; D. P. Hand; W. N. MacPherson

doi:10.1117/12.2059869

2 June 2014 Optical fibre cantilever sensor for biological application

J. Li, Y. X. Zhou, G. Patterson, W. M. Shu, R. R. J. Maier, R. Fowler, D. P. Hand, W. N. MacPherson

Proceedings Volume 9157, 23rd International Conference on Optical Fibre Sensors; 91575I (2014) https://doi.org/10.1117/12.2059869
Event: OFS2014 23rd International Conference on Optical Fiber Sensors, 2014, Santander, Spain

Abstract

Micro-cantilever sensors have shown great promise in a wide range of application are as including chemical and biological sensing. However, many of these devices are based upon a sensor ‘chip’ that requires careful alignment between the cantilever and the read-out system, which can be challenging. Furthermore, optical interrogation typically involves a bulky free-space system. Optical fibre addressed cantilevers have been reported previously in the literature and in this paper we propose techniques to design and fabricate polymer micro-cantilevers for attachment onto the end of standard single mode fibres using laser machining. Low-cost optical sources and a fibre coupled spectrometer are employed to monitor the cantilever deflection and therefore observe biological binding between a species of interest and an activated cantilever. Proof-of-concept experiments show that the sensor is capable of detecting pathogen concentration with down to a level of 10⁵cfu/ml.

Citation Download Citation

J. Li, Y. X. Zhou, G. Patterson, W. M. Shu, R. R. J. Maier, R. Fowler, D. P. Hand, and W. N. MacPherson "Optical fibre cantilever sensor for biological application", Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 91575I (2 June 2014); https://doi.org/10.1117/12.2059869

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