Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation

Hiroyuki Fujii; Shinpei Okawa; Ken Nadamoto; Eiji Okada; Yukio Yamada; Yoko Hoshi; Masao Watanabe

doi:10.1117/12.2079265

10 March 2015 Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation

Hiroyuki Fujii, Shinpei Okawa, Ken Nadamoto, Eiji Okada, Yukio Yamada, Yoko Hoshi, Masao Watanabe

Author Affiliations +

Proceedings Volume 9333, Biomedical Applications of Light Scattering IX; 933313 (2015) https://doi.org/10.1117/12.2079265
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Accurate modeling and efficient calculation of photon migration in biological tissues is requested for determination of the optical properties of living tissues by in vivo experiments. This study develops a calculation scheme of photon migration for determination of the optical properties of the rat cerebral cortex (ca 0.2 cm thick) based on the three-dimensional time-dependent radiative transport equation assuming a homogeneous object. It is shown that the time-resolved profiles calculated by the developed scheme agree with the profiles measured by in vivo experiments using near infrared light. Also, an efficient calculation method is tested using the delta-Eddington approximation of the scattering phase function.

Citation Download Citation

Hiroyuki Fujii, Shinpei Okawa, Ken Nadamoto, Eiji Okada, Yukio Yamada, Yoko Hoshi, and Masao Watanabe "Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation", Proc. SPIE 9333, Biomedical Applications of Light Scattering IX, 933313 (10 March 2015); https://doi.org/10.1117/12.2079265

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