Liquid-crystal-based biosensing beyond texture observations

Mon-Juan Lee; Chi-Hao Lin; Wei Lee

doi:10.1117/12.2187818

5 September 2015 Liquid-crystal-based biosensing beyond texture observations

Mon-Juan Lee, Chi-Hao Lin, Wei Lee

Proceedings Volume 9565, Liquid Crystals XIX; 956510 (2015) https://doi.org/10.1117/12.2187818
Event: SPIE Organic Photonics + Electronics, 2015, San Diego, California, United States

Abstract

The texture observation has long been the core technique in liquid crystal (LC)-based biosensing. One of the drawbacks of this observational means is the difficulty in quantitative analysis. In this invited paper, we report on our recent attempt to improve the LC-based biosensing technique through the analysis of bovine serum albumin (BSA), a protein standard commonly used in the assay of protein concentration. We propose to overcome the technical limitations in the analysis of LC-based biosensors by considering alternative measuring schemes. By means of the induced changes in electro-optical properties of LCs in the presence of different concentrations of BSA, novel quantitative techniques specific for LC-based biosensors are developed.

Citation Download Citation

Mon-Juan Lee, Chi-Hao Lin, and Wei Lee "Liquid-crystal-based biosensing beyond texture observations", Proc. SPIE 9565, Liquid Crystals XIX, 956510 (5 September 2015); https://doi.org/10.1117/12.2187818

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