CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC11937 > Article
Presentation
7 March 2022 Micromotor OCTA-FLIM catheter for cancer screening
Eric Brace, Scott Bernard, Jeanie Malone, Adrian Tanskanen, Anthony Lee, Catherine Poh, Pierre Lane
Author Affiliations +
Proceedings Volume PC11937, Endoscopic Microscopy XVII; PC1193706 (2022) https://doi.org/10.1117/12.2609113
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Fluorophores associated with early development of cancer (FAD, NADH, collagen) and abnormalities in microvessel structure have been shown to correlate with oral cancer progression. Co-registered imaging approaches using optical coherence tomography (OCT) and fluorescence imaging techniques have demonstrated promise in assessing these biomarkers, but current endoscopic approaches are limited in specificity. We propose that a micromotor-based OCT angiography and fluorescence-lifetime imaging microscopy (FLIM) may provide a suitable biopsy guidance tool for oral cancer screening. We present initial work towards implementing these modalities with a micromotor catheter system, validated with phantoms. Performance is compared to our existing OCT-autofluorescence system.
Conference Presentation
© (2022) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Eric Brace, Scott Bernard, Jeanie Malone, Adrian Tanskanen, Anthony Lee, Catherine Poh, and Pierre Lane "Micromotor OCTA-FLIM catheter for cancer screening", Proc. SPIE PC11937, Endoscopic Microscopy XVII, PC1193706 (7 March 2022); https://doi.org/10.1117/12.2609113
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Cancer
Angiography
Luminescence
Optical coherence tomography
Biopsy
Fluorescence lifetime imaging
Multimodal imaging
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top