The future of mid-infrared sensors: from exhaled breath analysis to in-vivo biodiagnostics

Boris Mizaikoff

doi:10.1117/12.2616001

7 March 2022 The future of mid-infrared sensors: from exhaled breath analysis to in-vivo biodiagnostics

Boris Mizaikoff

Proceedings Volume PC11957, Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry; PC119570H (2022) https://doi.org/10.1117/12.2616001
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Vibrational spectroscopies and especially infrared spectroscopy play an increasing in modern biodiagnostics. Applications range from non-invasive exhaled breath analysis to in-vivo assessment of cartilage damage rendering mid-infrared (MIR; 3-20 µm) photonics tools among the most flexible molecular sensing platforms nowadays available. With the emergence of quantum and interband cascade laser technology, the hybrid on-chip integration of entire MIR sensing device es is conceivable leading to IR-lab-on-chip systems. The inherent molecular selectivity of MIR signatures enables studying small (e.g., volatile organic compounds; VOCs) in the gas phase, as well as large biomacromolecules (e.g., proteins) in the liquid phase with unsurpassed detail in a label-free and non-destructive fashion in real-world complex mixtures if clinical relevance. Latest MIR photonic technology will be complemented by highlight applications demonstrating the utility of next-generation MIR photonics.

Conference Presentation

Citation Download Citation

Boris Mizaikoff "The future of mid-infrared sensors: from exhaled breath analysis to in-vivo biodiagnostics", Proc. SPIE PC11957, Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry, PC119570H (7 March 2022); https://doi.org/10.1117/12.2616001

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