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17 March 2023 A melanoma cancer screening framework based on depth-resolved light scattering
Motasam Majedy, Nandan K. Das, Johannes Johansson, Rolf B. Saager
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Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC1235205 (2023) https://doi.org/10.1117/12.2649645
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
A non-invasive means to determine lesion depth (I.e. Breslow Thickness) and an indirect, lesion-specific assessment of cellular morphology could substantially improve the efficacy of melanoma screening. Such applications would be of great benefit in aiding diagnosis, reducing the number of unnecessary biopsies, and improving treatment options for patients. Using Spatial Frequency Domain Imaging (SFDI), we have developed a spectral method to isolate depth-specific scattering properties and hence, differentiate pigmented lesion volumes from underlying tissue by its structural morphology. This method was evaluated on solid phantoms that emulate the optical properties of suspect pigmented lesions over multiple thicknesses.
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Motasam Majedy, Nandan K. Das, Johannes Johansson, and Rolf B. Saager "A melanoma cancer screening framework based on depth-resolved light scattering", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC1235205 (17 March 2023); https://doi.org/10.1117/12.2649645
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KEYWORDS
Light scattering
Melanoma
Cancer
Scattering
Tissues
Biopsy
Skin
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