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17 March 2023 Correlation of MRI and contrast-enhanced ultrasound imaging and radical prostatectomy specimens following transperineal focal laser ablation for prostate cancer
Mitra Almasian, Luigi A. Van Riel, Rob A. A. van Kolleburg, Ton G. van Leeuwen, Theo M. de Reijke, Daniel M. de Bruin, Jorg R. Oddens, Jan-Erik Freund, Auke Jager, Marc W. Engelbrecht, Ruth Smit, Elise Bekers, Jakko A. Nieuwenhuijzen, Pim J. van Leeuwen, Henk van der Poel, Harrie P. Beerlage
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Proceedings Volume PC12353, Advanced Photonics in Urology 2023; PC123530A (2023) https://doi.org/10.1117/12.2650642
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Transperineal focal laser ablation (TPLA) has the potential to obtain oncological control, while sparing nearby tissue to preserve continence and erectile function with a low toxicity profile. However, registration and prediction of the ablation zone is essential for TPLA to become a clinal standard of care treatment. In this study we investigated the capability of MRI and CEUS to image the treated volume. We show that the treatment effects of TPLA can reliably be visualized using these techniques and that the results are in good agreement with histopathology. These results are essential first steps towards improved planning and performance of TPLA.
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Mitra Almasian, Luigi A. Van Riel, Rob A. A. van Kolleburg, Ton G. van Leeuwen, Theo M. de Reijke, Daniel M. de Bruin, Jorg R. Oddens, Jan-Erik Freund, Auke Jager, Marc W. Engelbrecht, Ruth Smit, Elise Bekers, Jakko A. Nieuwenhuijzen, Pim J. van Leeuwen, Henk van der Poel, and Harrie P. Beerlage "Correlation of MRI and contrast-enhanced ultrasound imaging and radical prostatectomy specimens following transperineal focal laser ablation for prostate cancer", Proc. SPIE PC12353, Advanced Photonics in Urology 2023, PC123530A (17 March 2023); https://doi.org/10.1117/12.2650642
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KEYWORDS
Magnetic resonance imaging
Laser ablation
Ultrasonography
Prostate cancer
Principal component analysis
3D image processing
3D modeling
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