Parallel interferometric near-infrared spectroscopy (πNIRS) monitors blood flow and absorption changes of the human brain in-vivo

Dawid Borycki; Saeed Samaei; Klaudia Nowacka

doi:10.1117/12.2649320

7 March 2023 Parallel interferometric near-infrared spectroscopy (πNIRS) monitors blood flow and absorption changes of the human brain in-vivo

Dawid Borycki, Saeed Samaei, Klaudia Nowacka

Author Affiliations +

Proceedings Volume PC12378, Dynamics and Fluctuations in Biomedical Photonics XX; PC1237806 (2023) https://doi.org/10.1117/12.2649320
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Interferometric near-infrared spectroscopy (iNIRS) noninvasively measures the optical and dynamical properties of the human brain in vivo. However, iNIRS uses single-mode fibers, which reduces the detected light throughput. Here, we demonstrate the parallel interferometric near-infrared spectroscopy (πNIRS) to overcome this limitation. In πNIRS we use multi-mode fibers for light collection and a high-speed, two-dimensional camera for light detection. With more than 8000 parallel channels, we can sense the cerebral blood flow and absorption changes with only 2-10 msec integration time (~100-500x faster than conventional iNIRS). This capability enabled us to monitor prefrontal cortex activation in humans in vivo.

Conference Presentation

Citation Download Citation

Dawid Borycki, Saeed Samaei, and Klaudia Nowacka "Parallel interferometric near-infrared spectroscopy (πNIRS) monitors blood flow and absorption changes of the human brain in-vivo", Proc. SPIE PC12378, Dynamics and Fluctuations in Biomedical Photonics XX, PC1237806 (7 March 2023); https://doi.org/10.1117/12.2649320

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