Sum-frequency generation and the CH stretching modes in collagen type I

Yryx Luna Palacios; Israel Rocha Mendoza; David Knez; Salile Khandani; Evan P. Garcia; Eric O. Potma

doi:10.1117/12.3003418

13 March 2024 Sum-frequency generation and the CH stretching modes in collagen type I

Yryx Luna Palacios, Israel Rocha Mendoza, David Knez, Salile Khandani, Evan P. Garcia, Eric O. Potma

Proceedings Volume PC12839, Biomedical Vibrational Spectroscopy 2024: Advances in Research and Industry; PC128390M (2024) https://doi.org/10.1117/12.3003418
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Vibrational sum-frequency generation (SFG) microscopy is a highly sensitive and selective optical imaging technique capable of retrieving information on the molecular structure of proteins. In this study, we determined the achiral tensor elements Х_ijk^((2)) associated with the the symmetric and asymmetric methylene (CH2) stretching modes of collagen type I through polarization-sensitive SFG measurements, and compared the results with computational modeling based on the crystal structure information from the Protein Data Bank. These findings contribute to our understanding of protein structure and pave the way to predict proteins' non-linear optical properties directly from their crystal structure.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Yryx Luna Palacios, Israel Rocha Mendoza, David Knez, Salile Khandani, Evan P. Garcia, and Eric O. Potma "Sum-frequency generation and the CH stretching modes in collagen type I", Proc. SPIE PC12839, Biomedical Vibrational Spectroscopy 2024: Advances in Research and Industry, PC128390M (13 March 2024); https://doi.org/10.1117/12.3003418

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Sum frequency generation

Collagen

Vibration

Proteins

Chemical elements

Crystals

Mid-IR

Show All Keywords

Keywords/Phrases

Search In:

Publication Years