Spatial light correlations improve sensitivity of the noninvasive cerebral blood flow sensing in humans in vivo

Klaudia Nowacka; Saeed Samaei; Michał Dąbrowski; Dawid Borycki

doi:10.1117/12.3003657

13 March 2024 Spatial light correlations improve sensitivity of the noninvasive cerebral blood flow sensing in humans in vivo

Klaudia Nowacka, Saeed Samaei, Michał Dąbrowski, Dawid Borycki

Author Affiliations +

Proceedings Volume PC12841, Dynamics and Fluctuations in Biomedical Photonics XXI; PC128410E (2024) https://doi.org/10.1117/12.3003657
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Optical methods can provide noninvasive approach for continuous cerebral blood flow (CBF) monitoring in humans in vivo. Diffuse correlation spectroscopy (DCS) is an established modality for qualitative CBF monitoring. DCS decodes the CBF from an analysis of the temporal correlations of the light scattered by the tissue. This, however, requires ultra-fast, generating vast amount of data to be processed. Instead of rapidly sensing temporal correlations, we can decode sample dynamics by quantifying speckle contrast, which is inversely proportional to the blood flow. Here, we analyze such an approach in the continuous-wave parallel interferometric near-infrared spectroscopy (CW-πNIRS)

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Klaudia Nowacka, Saeed Samaei, Michał Dąbrowski, and Dawid Borycki "Spatial light correlations improve sensitivity of the noninvasive cerebral blood flow sensing in humans in vivo", Proc. SPIE PC12841, Dynamics and Fluctuations in Biomedical Photonics XXI, PC128410E (13 March 2024); https://doi.org/10.1117/12.3003657

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