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Unstable plaques in the carotid artery are a leading cause of ischemic stroke, resulting in numerous deaths globally. A reliable predictor of rupture risk is plaque composition. Photoacoustic Imaging is a promising imaging modality suitable for this task. Quantifying Photoacoustic Imaging poses challenges as it requires knowledge of complex light propagation in tissue. Our approach utilizes arterial blood as a fluence marker to determine the optical properties of the plaque. This proposed method involves optical and acoustic modeling and iterative updating of the optical properties. We characterized the proposed technique by varying different parameters in digital phantoms.
Max T. Rietberg,Anjali Thomas, andKalloor Joseph Francis
"Quantifying photoacoustic model utilizing blood as a fluence marker for carotid plaque composition imaging", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC128422X (13 March 2024); https://doi.org/10.1117/12.3002698
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Max T. Rietberg, Anjali Thomas, Kalloor Joseph Francis, "Quantifying photoacoustic model utilizing blood as a fluence marker for carotid plaque composition imaging," Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC128422X (13 March 2024); https://doi.org/10.1117/12.3002698