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13 March 2024 On-chip chemiluminescence biosensor for detection of surface contamination
Meruyert Imanbekova, Reza Abbasi, Sebastian Wachsmann-Hogiu
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Proceedings Volume PC12858, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI; PC1285809 (2024) https://doi.org/10.1117/12.3009613
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
A novel on-chip chemiluminescence biosensor is developed to assess cleanliness of the solid surfaces. The sensor is based on ATP-mediated chemiluminescence detection. It provides high-sensitivity detection of surface contamination due to improved photon collection efficiency. The results show the dependence of the bioluminescence enhancement on ATP concentration. We report the limit of detection of the biosensor. We demonstrate the use of the biosensor for real sample analysis to assess surface contamination of the laboratory and office equipment. This suggests the use of the biosensor in practical applications such as the food processing industry, laboratory environments, and health care settings.
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Meruyert Imanbekova, Reza Abbasi, and Sebastian Wachsmann-Hogiu "On-chip chemiluminescence biosensor for detection of surface contamination", Proc. SPIE PC12858, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI, PC1285809 (13 March 2024); https://doi.org/10.1117/12.3009613
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KEYWORDS
Biosensors
Chemiluminescence
Contamination
Acquisition tracking and pointing
Optical sensors
Pathogens
Portability
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