Lensless microendoscope for quantitative phase imaging with flexible working distance

Jie Zhang; Jiawei Sun; Nektarios Koukourakis; Jürgen Czarske

doi:10.1117/12.3022299

18 June 2024 Lensless microendoscope for quantitative phase imaging with flexible working distance

Jie Zhang, Jiawei Sun, Nektarios Koukourakis, Jürgen Czarske

Proceedings Volume PC12996, Unconventional Optical Imaging IV; PC1299606 (2024) https://doi.org/10.1117/12.3022299
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

Quantitative phase imaging (QPI) is essential in biomedicine and surface inspection for its 3D high-resolution imaging. Conventional QPI methods, hindered by large optical setups, face challenges in small spaces like in-vivo imaging of cancer tissues. To combat this, our study introduces a novel, ultra-thin, lensless microendoscope using multicore fiber, enabling effective QPI even in limited spaces. This device captures real-time holograms, reconstructing complex light fields with automatic digital refocusing, achieving up to 15 nm axial and 1-micron spatial resolution. Its compact 0.5 mm design significantly enhances access to restricted areas, revolutionizing surface inspection and in-vivo clinical diagnostic imaging.

Conference Presentation

Citation Download Citation

Jie Zhang, Jiawei Sun, Nektarios Koukourakis, and Jürgen Czarske "Lensless microendoscope for quantitative phase imaging with flexible working distance", Proc. SPIE PC12996, Unconventional Optical Imaging IV, PC1299606 (18 June 2024); https://doi.org/10.1117/12.3022299

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