Ali Jaafar,1 Abbas Albarazanchi,2 Firas S. Mohammed,2 Ahmed Al‑Haddad,2 Maxim E. Darvin,3 Tamás Váczi,1 Valery V. Tuchinhttps://orcid.org/0000-0001-7479-2694,4 Miklós Veres1
1Institute of Solid State Physics and Optics, Wigner Research Ctr. for Physics (Hungary) 2Mustansiriyah Univ. (Iraq) 3Independent Researcher (Germany) 4Institute of Physics and Science Medical Ctr., Saratov State Univ. (Russian Federation)
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The ex vivo porcine lung tissue exposure to nicotine-flavour free e-liquid was examined in-depth using confocal Raman micro-spectroscopy. It was found that the lung-related Raman bands and autofluorescence intensities were enhanced after exposure to e-liquid for all depths and treatment time (first and second treatments) due to the optical clearing effect of glycerol and propylene glycol as an OC agent. The nicotine-flavour free e-liquids that contain glycerol and propylene glycol could potentially be used in clinical protocols for lung disease discrimination in-depth using Raman-based in vivo bronchoscopy due to light scattering reduction as an optical clearing agent.
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Ali Jaafar, Abbas Albarazanchi, Firas S. Mohammed, Ahmed Al‑Haddad, Maxim E. Darvin, Tamás Váczi, Valery V. Tuchin, Miklós Veres, "Impact of e-cigarette vape on ex vivo porcine lung optical properties by confocal Raman micro-spectroscopy study," Proc. SPIE PC13010, Tissue Optics and Photonics III, PC1301001 (19 June 2024); https://doi.org/10.1117/12.3017480