Quantification of scattering changes using polarization-sensitive optical coherence tomography

Sang-Won Lee; Jin-Ho Kang; Ji-Yeong Yoo; Moon-Sik Kang; Jung-Taek Oh; Beop-Min Kim

doi:10.1117/1.2976430

1 September 2008 Quantification of scattering changes using polarization-sensitive optical coherence tomography

Sang-Won Lee, Jin-Ho Kang, Ji-Yeong Yoo, Moon-Sik Kang, Jung-Taek Oh, Beop-Min Kim

Author Affiliations +

Journal of Biomedical Optics, Vol. 13, Issue 5, 054032 (September 2008). https://doi.org/10.1117/1.2976430

Abstract

We demonstrate that changes in the degree of polarization (DOP) depend on changes in the scattering coefficient, and they can be quantified by using a polarization-sensitive optical coherence tomography (PS-OCT) system. We test our hypothesis using liquid and solid phantoms made from Intralipid suspensions and gelatin, respectively. We also quantify the DOP changes with depth caused by changes in the concentration of scatterers in the liquid and solid phantoms. It is clearly shown that the DOP change has a linear relationship with the scattering change. In our previous study, we showed that the axial slope of the DOP is different between normal and pathologic cervical tissues. Our results demonstrate that the quantification of the axial DOP slope can be used for the systematic diagnosis of certain tissue pathology.

©(2008) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Sang-Won Lee, Jin-Ho Kang, Ji-Yeong Yoo, Moon-Sik Kang, Jung-Taek Oh, and Beop-Min Kim "Quantification of scattering changes using polarization-sensitive optical coherence tomography," Journal of Biomedical Optics 13(5), 054032 (1 September 2008). https://doi.org/10.1117/1.2976430

Published: 1 September 2008

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Cited by 12 scholarly publications.

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KEYWORDS

Scattering

Tissues

Light scattering

Optical coherence tomography

Liquids

Solids

Polarization

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