Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter

Christine P. Fleming; Hui Wang; Kara J. Quan; Andrew M. Rollins

doi:10.1117/1.3459134

1 May 2010 Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter

Christine P. Fleming, Hui Wang, Kara J. Quan, Andrew M. Rollins

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Journal of Biomedical Optics, Vol. 15, Issue 3, 030516 (May 2010). https://doi.org/10.1117/1.3459134

Abstract

Radio-frequency ablation (rfa) is the standard of care for the treatment of cardiac arrhythmias; however, there are no direct measures of the successful delivery of ablation lesions. Optical coherence tomography (OCT) imaging has the potential to provide real-time monitoring of cardiac rfa therapy, visualizing lesion formation and assessing tissue contact in the presence of blood. A rfa-compatible forward-imaging conical scanning probe is prototyped to meet this need. The forward-imaging probe provides circular scanning, with a 2-mm scan diameter and 30-µm spot size. During the application of rf energy, dynamics are recorded at 20 frames per second with a 40-kHz A-line rate. Real-time monitoring of cardiac rfa lesion formation and imaging in the presence of blood is demonstrated ex vivo in a swine left ventricle with a forward, flexible, circular scanning OCT catheter.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Christine P. Fleming, Hui Wang, Kara J. Quan, and Andrew M. Rollins "Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter," Journal of Biomedical Optics 15(3), 030516 (1 May 2010). https://doi.org/10.1117/1.3459134

Published: 1 May 2010

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